14 people killed in Syria airstrike.

An airstrike in Syria has destroyed a hospital in Aleppo supported by the international charity Doctors Without Borders, killing at least 14 people.

Among the dead were two doctors, including Aleppo’s last pediatrician working in rebel-controlled areas. News accounts reported three children were also killed in the night-time raid overnight into Thursday.

The attack came amidst a marked increase in violence in Aleppo, with nearly 200 killed in the past week in clashes between government forces supporting embattled President Bashar al-Assad and rebel groups trying to overthrow his regime. The rebels have bombarded government-controlled neighborhoods with rocket and artillery fire, while Syrian jetfighters have conducted air raids.

The fighting has left the country’s supposed cease-fire in shambles, with United Nations envoy Staffan de Mistura saying a so-called cessation of hostilities agreement was “barely alive.”

The pro-government newspaper Al-Watan said the Syrian army is now set for a “decisive battle” against rebel strongholds in Aleppo. An editorial in the newspaper said it was time for government forces to seize Aleppo, where 250,000 people live, and said the assault “will not take long to begin, nor to finish.”

The head of Doctors Without Borders’ Syrian mission, Muskilda Zancada, condemned the attack on Al Quds hospital, calling it an “outrageous targeting.”

“This devastating attack has destroyed a vital hospital in Aleppo, and the main referral center for pediatric care in the area,” Zancada said. “Where is the outrage among those with the power and obligation to stop this carnage?”

Humanitarian crisis looming

With the Aleppo violence intensifying, Jan Egeland, the chair of the U.N. humanitarian task force on Syria, said, “I cannot express how high the stakes are for the next hours and days.”

The British-based Syrian Observatory for Human Rights said that least 38 civilians were killed in Aleppo and 40 more wounded in new fighting Thursday.

The International Committee of the Red Cross warned that Aleppo is on the brink of a humanitarian crisis

On Wednesday, Russia asked the U.N. Security Council to impose sanctions on a Syrian opposition group that has been heavily involved in peace talks.

Ambassador Vitaly Churkin accused Jaish al-Islam, and a second rebel group, Ahrar al-Sham, of being “closely connected” to Islamic State and al-Qaida.

Jaish-al-Islam is a top member of the Western and Arab-backed High Negotiations Committee, which the U.N. set up last year to work out a political solution to the Syrian civil war.